Going down the wrong path
Why I openly question the "New Normal" or "New life style"
Time for Pause
Thoughts from two scientists1. John P. A. Ioannidis, Professor of Medicine, Stanford University
Why Most Published Research Findings Are False2. Prof. Honjo Tasuku's interview with NHK after the announcement of his receiving the Nobel prize for Medicine/Physiology.
Published research findings are sometimes refuted by subsequent evidence, with ensuing confusion and disappointment. Refutation and controversy is seen across the range of research designs, from clinical trials and traditional epidemiological studies [1–3] to the most modern molecular research [4,5]. There is increasing concern that in modern research, false findings may be the majority or even the vast majority of published research claims [6–8]. However, this should not be surprising. It can be proven that most claimed research findings are false. Here I will examine the key factors that influence this problem and some corollaries thereof.
The interview originally appeared in an NHK report, but is no longer available. However, an archived version can be found here
I have taken the liberty to paraphrase Prof. Honjo's answer in English. Any possible errors in interpreting Prof. Honjo's statements are mine.
Q: What do you keep in mind, what is your motto?
A: "Scientific research, to me, involves a curiosity to know about something. Further, I am not a person who believes in anything easily. People in the mass media often revere scientific work appearing in Nature and Science journals, but I am of the opinion that 90% of the research papers published in Nature and Science are incorrect; perhaps, only 10% stands the test of time. Thus, I do not easily accept what is written in the papers or what they conclude. I persevere in investigations of a scientific fact until I am convinced of its veracity. That is how I approach science. In other words, I think with my own head and work until the facts convince me.